Significance of microvessel density in prostate cancer core biopsy

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Significance of microvessel density in prostate cancer core biopsy.

BACKGROUND/AIM In prostate tumors, angiogenesis, measured as microvessel density, is associated with tumor stage and Gleason score. The aim of this study was determine neovascularization of prostatic adenocarcinomas in core biopsies and corresponding prostatectomies. METHODS The study population included 61 patients who underwent radical prostatectomy (RP) for localized prostate carcinoma pat...

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Clinical significance of microvessel density and proliferation in prostate cancer core biopsy.

PURPOSE To investigate the microvessel density (MVD) and proliferation in prostate cancer (PC) core biopsies. METHODS Core biopsy samples of PC tissue from 45 patients were routinely processed and embedded in paraffin. The samples of PC formed the investigated group (n=25), while samples of benign prostatic hyperplasia (BPH) served as controls (n=20). From paraffin blocks, 3-5 μm-thick sectio...

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Augmented mast cell infiltration and microvessel density in prostate cancer

AIM OF THE STUDY Recent investigations have taken into account the role of mast cells in prostate cancer formation, analyzing their dual functions (as tumour growth promoters and tumour growth inhibitors). The aim of our study was to compare mast cell infiltration and microvessel density in prostate cancer and in benign prostate hyperplasia. We also attempted to find possible relationships amon...

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To investigate the role of angiogenesis in multiple myeloma (MM), bone marrow biopsy from 75 adults with newly diagnosed, untreated MM were evaluated. Microvessels were scored in at least 3 areas ( x 200 fields) of the highest microvessel density in representative sections of each bone marrow specimen using immunohistochemistry for CD34. Prognostic variables were also evaluated for the overall ...

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ژورنال

عنوان ژورنال: Military Medical and Pharmaceutical Journal of Serbia

سال: 2015

ISSN: 0042-8450,2406-0720

DOI: 10.2298/vsp131111004s